Vicious Cycles in Chronic Fatigue Syndrome and Fibromyalgia. Leaky Gut, the Sympathetic Nervous Syst

Published: 23rd July 2009
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New research from Dr Meirlier at Protea Biopharma in Holland has recently revealed another vicious cycle of the appalling knock on effects that we see in Chronic Fatigue (CFS) and Fibromyalgia patients.

These same vicious cycles result ultimately in the baffling array of symptoms that patients present and in turn make treatment so complicated, difficult and frustrating for sufferers, their doctors and complementary therapists.

But with every passing month we are getting ever closer to understanding the core system insults and failures and with the improved knowledge comes improved treatment strategies and advanced protocols based on addressing real organic changes in the body.

This latest research is particularly welcome and aligns itself with the vicious cycle of Chronic Fatigue and Fibromyalgia theories.

It also confirms and reinforces my own successful CFS methods and treatment protocol.

It also allows me to declare an additional improvement to my protocol which will yield further improvement.

In so many CFS and Fibromyalgia patients digestive, gut and intestinal problems are a mainstay of the symptoms presented.

So many patients declare some form of digestive, intestinal or bowel dysfunction pre or post onset of the recognized trigger for their current condition.

In the early stages of CFS and Fibromyalgia illnesses many patients will have attempted broad spectrum antibiotic regimes aimed at wholesale elimination of dangerous or "bad" bacteria from the gut.

Subsequently these patients may not have followed up the broad spectrum antibiotic treatment with a suitable course of probiotics and/ or prebiotics.

Some CFS and Fibromyalgia patients may have had severe gut viruses like Epstein Barr or Coxsackie strains.

Some patients have descended into Chronic Fatigue and Fibromyalgia with the recognized trigger being an apparent episode of food poisoning or ingesting some other foreign chemical or toxin.

Oftentimes a long history of Irritable Bowel Syndrome (IBS) or Crohns Disease can precede the onset of Chronic Fatigue, or the muscular and joint symptoms associated with a diagnosis of Fibromyalgia.

This digestive and intestinal symptoms often lead to the diagnosis of 'Leaky Gut'.

The theory behind Leaky Gut is that large immunologically active cells can pass across the weakened intestinal wall of the patients gut and enter the bloodstream where they are identified as alien to the host and activate a powerful immune response.

As the immune system (which is largely based around the intestines) reacts continuously in this way sufferers develop a variety of allergies to various foods and substances.

Foods that present particular interest to a Leaky Gut are dairy, gluten, grain, egg and yeast type foods.

A host of airborne toxins are also implicated in allergies.

By intensive research into the Leaky Gut theory Dr Meirlier identified that a Leaky Gut reliably produces a by-product gas - Hydrogen Sulphide.

This reaction appears consistently throughout 80 to 90% of recognized Fibromyalgia and CFS patients with digestive involvement.

This gas is harmless in small quantities but very toxic in large quantities as produced by CFS sufferers.

Dr Meirlier's research revealed the following data related to excessive H2S production in CFS/ Fibromyalgia sufferers:

' Potent neuro toxin.
' Light intolerance.
' Intolerance to noise.
' Mitochondrial dysfunction.
' Depression of the immune system at a cellular level.
' Neutropenia and low numbers of CD8+ lymphocytes.
' Increased bacterial production the gut.
' Increased ROS production by the liver.
' Retention of heavy metals particularly mercury in the body.
' Mercury is neurotoxic, induces apoptosis and interferes with aerobic metabolism.
' In severely ill M.E *, sufferers can develop aberrant prions which can cause havoc with energy metabolism.

* CFS/ Fibromyalgia are commonly referred to as Myalgic Encephalomyelitis in Europe (M.E).

H2S is excreted via the liver and kidneys to the urine and so has lead to the formation of Dr Meirliers test for H2S in first morning urine.

The early results are very encouraging.

Most importantly this test can give sufferers yet another lead in tackling the multi factorial failures that all need tackling simultaneously in order to reverse what are serious organic fatigue spectrum illnesses.

The reason tackling the Leaky Gut may be so important is that it could in some cases be directly at the core of a knock-on flow, a downward spiral of symptoms further down a long chain that eventually results in mitochondrial failure.

We know already that the sympathetic nervous system is in disarray in fatigue patients ' we also know that these systems are largely situated around the gut, the intestines, digestive system and bowel.

In the next part of this series i examine the effects of Leaky Gut and H2S on the Sympathetic nervous system, the direct implications for H2S on the Hypothalamic Pituitary Axis (HPA) and the associated knock on effects for the entire endocrine system and immunity.

Finally I discuss how to treat, prevent, and repair the damage caused by this downward spiral.

Read Dr Mark Shaw's Revolutionary Research into CFS and Fibromyalgia -
Practical, Affordable, Effective, Daily Protocol and Recovery Strategy.
Free Articles and Advice -
How to Beat Fibromyalgia and Chronic Fatigue in 30 Days =>

Copyright - 22/07/2009.

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